Viral enzymes — Which virus carries the enzyme neuraminidase as a surface glycoprotein?

Introduction:Some viruses package or express characteristic enzymes and glycoproteins that are central to their life cycle and serve as drug targets. Neuraminidase is a hallmark enzyme of influenza virions used in viral release from infected cells.

Given Data / Assumptions:

• We are asked to identify the virus associated with neuraminidase.
• Candidates include RNA and DNA viruses with distinct biology.

Concept / Approach:Influenza A and B have two major surface glycoproteins: hemagglutinin and neuraminidase. Neuraminidase cleaves terminal sialic acid residues, facilitating virion release and preventing reattachment to the same cell. This enzyme is the target of oseltamivir and zanamivir.

Step-by-Step Solution:

Verification / Alternative check:Drug classes named neuraminidase inhibitors are clinically used for influenza, confirming the association.

Why Other Options Are Wrong:

• HIV: carries reverse transcriptase, integrase, and protease, not neuraminidase.
• Epstein–Barr virus: herpesvirus with different glycoprotein set.
• Adenovirus: nonenveloped DNA virus without NA.

Common Pitfalls:Confusing neuraminidase with neuraminic acid binding by hemagglutinin; HA binds sialic acid, NA cleaves it.

Final Answer:Influenza virus