Difficulty: Easy
Correct Answer: Alcohol
Explanation:
Introduction / Context:Choosing the right chemical for high-level disinfection or sterilization requires awareness of sporicidal activity. Endospores resist many routine disinfectants; only a subset of chemicals are validated as sporicidal under correct conditions (concentration, temperature, exposure time).
Given Data / Assumptions:
Concept / Approach:Glutaraldehyde and formaldehyde (aldehydes) crosslink proteins and nucleic acids, achieving sporicidal effects with sufficient exposure. Ethylene oxide gas alkylates cellular constituents, sterilizing heat-sensitive equipment (including spores). Alcohols (ethyl, isopropyl) are excellent skin antiseptics but are not reliably sporicidal.
Step-by-Step Solution:
Identify aldehydes (glutaraldehyde, formaldehyde) as potential sterilants.Note ethylene oxide as a gaseous sterilant used for devices and catheters.Recognize alcohols as non-sporicidal; select as the exception.Verification / Alternative check:Disinfection guidelines categorize alcohols as intermediate-level (bactericidal, tuberculocidal, virucidal) but not sporicidal; aldehydes and ethylene oxide meet sporicidal criteria with validated protocols.
Why Other Options Are Wrong:
Common Pitfalls:Assuming strong “kill” on vegetative cells equals spore kill; spores need higher-level chemistry or heat.
Final Answer:Alcohol
Discussion & Comments