Phage gene expression timing — Which protein sets are typically synthesized from late mRNA during a lytic infection?

Difficulty: Easy

Correct Answer: All of the above

Explanation:


Introduction / Context:
Lytic phage infections proceed through an ordered transcriptional program: early genes for takeover and replication functions, and late genes for particle construction and release. Knowing which proteins appear from late mRNA clarifies phage biology and biotechnology applications.



Given Data / Assumptions:

  • Late gene expression follows genome replication.
  • Late mRNAs encode virion components and lysis machinery.
  • Some late proteins assist assembly but are not retained in the mature virion.


Concept / Approach:
From late mRNA, phages synthesize capsid and tail proteins (structural), assembly-helper proteins (scaffolding, chaperones), and lysis proteins (e.g., endolysins, holins) that mediate host cell rupture. Therefore, all listed categories are produced from late transcripts.



Step-by-Step Solution:

Recall early vs. late gene roles.Map late mRNA to structural, assembly, and lysis functions.Select “All of the above.”


Verification / Alternative check:
Well-characterized phages (e.g., T4) show this transcriptional order; late promoters drive structural and lysis genes.



Why Other Options Are Wrong:

  • Picking only one subset ignores the full scope of late-phase products.


Common Pitfalls:
Assuming lysis proteins are early; they are typically expressed late to time particle release.



Final Answer:
All of the above

Discussion & Comments

No comments yet. Be the first to comment!
Join Discussion