Difficulty: Easy
Correct Answer: Induction
Explanation:
Introduction / Context:
Temperate bacteriophages can integrate into the host genome as prophage and remain quiescent under the control of a phage-encoded repressor. Under stress, the prophage can be activated to enter the lytic cycle. This activation step is called induction and is central to understanding lysogeny–lysis switches.
Given Data / Assumptions:
Concept / Approach:
In models such as phage lambda, the CI repressor maintains latency. SOS responses (RecA-mediated) cleave the repressor, resulting in induction. The prophage excises, replicates, and packages its DNA, culminating in host lysis and virion release.
Step-by-Step Solution:
Define lysogeny vs. lytic growth.
Identify the control protein (repressor) that prevents lytic gene expression.
Recognize environmental triggers that disable repression.
Name the switch event: induction.
Verification / Alternative check:
Classic experiments show UV exposure of lysogens yields phage production after prophage excision, consistent with induction.
Why Other Options Are Wrong:
Infection precedes lysogeny; integration is the establishment step; repression maintains dormancy; packaging is a late lytic event, not the trigger.
Common Pitfalls:
Confusing “induction” with initial infection; the term specifically refers to reactivation of a prophage.
Final Answer:
Induction.
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