Genome location in eukaryotes — Identify all organelles that contain DNA in a typical eukaryotic cell

Difficulty: Easy

Correct Answer: Both (a) and (b)

Explanation:


Introduction:
Eukaryotic cells compartmentalize functions within organelles, and DNA is housed in specific locations. This question evaluates recognition of all eukaryotic sites that contain their own genetic material.


Given Data / Assumptions:

  • Typical animal cell context (though plant chloroplasts also contain DNA).
  • Organelles listed: nucleus, mitochondrion, vacuole, Golgi apparatus.


Concept / Approach:
Eukaryotes possess nuclear DNA enclosed by the nuclear envelope. Mitochondria also maintain circular DNA and a prokaryote-like translation system, consistent with the endosymbiotic origin. Vacuoles and the Golgi apparatus do not contain their own DNA.


Step-by-Step Solution:

1) Nucleus: primary repository of chromosomal DNA in linear chromosomes.2) Mitochondrion: contains mitochondrial DNA (mtDNA), encoding rRNAs, tRNAs, and key respiratory chain subunits.3) Vacuole: a membrane-bound storage and degradative compartment; no genome.4) Golgi: processing and sorting station for proteins/lipids; no genome.5) Therefore, the correct combined choice is nucleus and mitochondrion.


Verification / Alternative check:
In plants and algae, chloroplasts also contain DNA (cpDNA). If chloroplast were among options, it would be included; here it is not, so the best answer remains nucleus and mitochondrion.


Why Other Options Are Wrong:

  • Nucleus only: ignores mitochondrial DNA.
  • Mitochondrion only: ignores the main nuclear genome.
  • Vacuole: lacks DNA.
  • Golgi apparatus: lacks DNA, functions in post-translational processing and trafficking.


Common Pitfalls:
Assuming every membrane-bound compartment contains DNA; most organelles rely on nuclear-encoded proteins and do not carry genomes.


Final Answer:
Both (a) and (b).

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