Membrane models — According to the fluid mosaic model, what best describes the nature of biological membranes?

Difficulty: Easy

Correct Answer: the membrane is a highly mobile mixture of phospholipids and proteins

Explanation:


Introduction:
The fluid mosaic model is a cornerstone of membrane biology. This question assesses whether you can articulate the model's central idea: lateral fluidity of lipids and proteins forming a dynamic, heterogeneous mosaic.


Given Data / Assumptions:

  • Typical eukaryotic plasma membrane.
  • Key components: phospholipids and proteins; carbohydrates are present as glycoconjugates.


Concept / Approach:
In the model, a phospholipid bilayer provides a fluid matrix into which proteins are inserted. Proteins and many lipids diffuse laterally; composition varies by membrane domain and leaflet.


Step-by-Step Solution:

1) Identify structural basis: bilayer of amphipathic phospholipids ensures barrier properties and fluidity.2) Recognize protein dynamics: integral and peripheral proteins move laterally (subject to constraints such as cytoskeletal anchoring and lipid rafts).3) Synthesize statement that captures both mobility and mosaic composition.


Verification / Alternative check:
Experiments such as FRAP (fluorescence recovery after photobleaching) demonstrate lateral diffusion of membrane proteins and lipids, validating the fluid aspect of the model.


Why Other Options Are Wrong:

  • Proteins most common: by count and area, lipids dominate; proteins are abundant but not the majority by molecule number.
  • Structure from protein–water interactions: the bilayer self-assembles from lipid amphipathic properties, not primarily protein–water interactions.
  • Properties determined by phospholipids alone: protein composition strongly shapes function.
  • Rigid lattices: contradicts extensive evidence for mobility.


Common Pitfalls:
Equating fluidity with randomness; membranes have microdomains and cytoskeletal fences that regulate diffusion without eliminating overall fluid behavior.


Final Answer:
the membrane is a highly mobile mixture of phospholipids and proteins.

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