Plasmids — defining features: Which statement correctly describes bacterial plasmids in standard microbiology and genetics?

Difficulty: Easy

Correct Answer: Small, circular DNA molecules that can exist independently of chromosomes and are common in bacteria

Explanation:


Introduction / Context:
Plasmids are foundational tools and natural genetic elements. They explain many medically important phenotypes, from antibiotic resistance to toxin production, and are the backbone of cloning vectors.



Given Data / Assumptions:

  • We are considering naturally occurring bacterial plasmids.
  • Most plasmids are circular double-stranded DNA, with their own origin of replication.
  • Plasmids replicate independently of the bacterial chromosome but can be maintained within the same cell.


Concept / Approach:

A correct definition must capture DNA identity, typical topology (circular), and replicative independence. It must not conflate plasmids with cellular structures or wall/membrane components.



Step-by-Step Solution:

Exclude membrane-related descriptions; plasmids are nucleic acids, not membranes.Exclude “protoplast,” which refers to a cell stripped of its wall.Identify the accurate description: small, circular, independently replicating DNA molecules common in bacteria.Select the statement that matches these properties.


Verification / Alternative check:

Standard plasmid maps show ori sites, selectable markers, and multiple cloning sites; laboratory maintenance without chromosomal integration demonstrates replicative independence.



Why Other Options Are Wrong:

Protoplast is a cellular state, not a DNA element.

“Complex membrane structure” misidentifies the nature of plasmids.

“None of the above” is invalid because a correct description exists.



Common Pitfalls:

Assuming all plasmids are circular; a minority may be linear, but the standard definition emphasizes small circular dsDNA independent of the chromosome.



Final Answer:

Small, circular DNA molecules that can exist independently of chromosomes and are common in bacteria

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