Discussion
Home ‣ Biochemical Engineering ‣ Downstream Processing Comments
- Question
A typical tubular centrifuge has a bowl of 2 to 5 inch in diameter and 9 to 30 inch in height with a maximum rotating speed of
Options- A. 15,000 to 50,000 rpm
- B. 50,000 to 100,000 rpm
- C. 100,000 to 150,000 rpm
- D. 150,000 to 200,000 rpm
- Correct Answer
- 15,000 to 50,000 rpm
- 1. The solvent flux across the membrane can be expressed as (where A is the area, Lp is the membrane permeability, ? is the reflection point, ?p is applied pressure and ?? is the osmotic pressure)
Options- A. J = Lp(?p - ???)
- B. J/A = Lp(?p - ???)
- C. J = Lp/???
- D. J/A = Lp/?p Discuss
- 2. Concentration polarization can be reduced further by
Options- A. pre filtering the solution
- B. reducing the flow rate per unit membrane surface area
- C. back washing periodically
- D. all of the above Discuss
- 3. Selectivity can be expressed as
Options- A. ratio of the distribution coefficients in different solute
- B. mass fraction of the solute in the extract phase at equilibrium
- C. mass fraction of the solute in the raffinate phase
- D. ratio of the mass fraction of the solute in the extract phase to the raffinate phase Discuss
- 4. Start up expenses in a fermentation industry varies from
Options- A. 0-5% of the capital cost
- B. 10-15% of the capital cost
- C. 5-10% of the capital cost
- D. 15-20% of the capital cost Discuss
- 5. The purity of a solute collected between two times t1 and t2 during chromatographic separation can be calculated as
Options- A. amount of solute eluted - amount of impurity eluted
- B. amount of solute eluted / amount of impurity eluted
- C. amount of solvent eluted + amount of impurity eluted
- D. amount of solvent eluted / amount of impurity eluted Discuss
- 6. The disk centrifuge is the type of centrifuge used most often for bio separations due to its
Options- A. continuous operation
- B. lesser cost
- C. higher speed
- D. ease in operation Discuss
- 7. Which of the following is not the physical method for the cells rupturing?
Options- A. Milling
- B. Homogenization
- C. Ultrasonication
- D. Enzymatic digestion Discuss
- 8. The optimum wet solid content for the cell suspension for a bead mill is typically somewhere between
Options- A. 5-15% by volume
- B. 15-30% by volume
- C. 30-60% by volume
- D. 60-90% by volume Discuss
- 9. The effectiveness of a solvent can be measured by the
Options- A. distribution coefficients
- B. selectivity
- C. both (a) and (b)
- D. diffusivity Discuss
- 10. A system which require less solvent and produces a more concentrated extract phase, is desired with a
Options- A. large distribution coefficients
- B. small distribution coefficients
- C. very small distribution coefficients
- D. constant distribution coefficients Discuss
Downstream Processing problems
Search Results
Correct Answer: J = Lp(?p - ???)
Correct Answer: all of the above
Correct Answer: ratio of the distribution coefficients in different solute
Correct Answer: 5-10% of the capital cost
Correct Answer: amount of solute eluted / amount of impurity eluted
Correct Answer: lesser cost
Correct Answer: Enzymatic digestion
Correct Answer: 30-60% by volume
Correct Answer: both (a) and (b)
Correct Answer: large distribution coefficients
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