Downstream Processing problems
- 1. In antibiotic manufacturing processes, the fermentation time ranges from
Options- A. 2-3 weeks
- B. 1-2 weeks
- C. 4-5 weeks
- D. 2-4 weeks Discuss
Correct Answer: 4-5 weeks
- 2. Chromatography is based on the
Options- A. different rate of movement of the solute in the column
- B. separation of one solute from other constituents by being captured on the adsorbent
- C. different rate of movement of the solvent in the column
- D. any of the above Discuss
Correct Answer: different rate of movement of the solute in the column
- 3. A common filter medium is the cloth filter generally made of
Options- A. canvas
- B. synthetic fabrics
- C. metal or glass fiber
- D. all of these Discuss
Correct Answer: all of these
- 4. Maintenance cost varies from
Options- A. 0-4% of the capital cost
- B. 12-16% of the capital cost
- C. 4-8% of the capital cost
- D. 8-12% of the capital cost Discuss
Correct Answer: 4-8% of the capital cost
- 5. The stage wise operation of adsorption is called
Options- A. contact filtration
- B. conventional adsorption
- C. affinity adsorption
- D. ion exchange Discuss
Correct Answer: contact filtration
- 6. The purity of a solute collected between two times t1 and t2 during chromatographic separation can be calculated as
Options- A. amount of solute eluted - amount of impurity eluted
- B. amount of solute eluted / amount of impurity eluted
- C. amount of solvent eluted + amount of impurity eluted
- D. amount of solvent eluted / amount of impurity eluted Discuss
Correct Answer: amount of solute eluted / amount of impurity eluted
- 7. Start up expenses in a fermentation industry varies from
Options- A. 0-5% of the capital cost
- B. 10-15% of the capital cost
- C. 5-10% of the capital cost
- D. 15-20% of the capital cost Discuss
Correct Answer: 5-10% of the capital cost
- 8. Selectivity can be expressed as
Options- A. ratio of the distribution coefficients in different solute
- B. mass fraction of the solute in the extract phase at equilibrium
- C. mass fraction of the solute in the raffinate phase
- D. ratio of the mass fraction of the solute in the extract phase to the raffinate phase Discuss
Correct Answer: ratio of the distribution coefficients in different solute
- 9. Concentration polarization can be reduced further by
Options- A. pre filtering the solution
- B. reducing the flow rate per unit membrane surface area
- C. back washing periodically
- D. all of the above Discuss
Correct Answer: all of the above
- 10. The solvent flux across the membrane can be expressed as (where A is the area, Lp is the membrane permeability, ? is the reflection point, ?p is applied pressure and ?? is the osmotic pressure)
Options- A. J = Lp(?p - ???)
- B. J/A = Lp(?p - ???)
- C. J = Lp/???
- D. J/A = Lp/?p Discuss
Correct Answer: J = Lp(?p - ???)
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