History of staining – discovery credit: Gram staining was introduced in 1884 by which scientist, whose surname now names the method?

Difficulty: Easy

Correct Answer: Hans Christian Gram

Explanation:


Introduction / Context:
Eponymous methods in microbiology often honor the original discoverers. Knowing the correct historical attribution prevents confusion with other notable figures in medical microbiology.


Given Data / Assumptions:

  • The year 1884 is associated with the original Gram stain publication.
  • Multiple distractors are prominent microbiologists or plausible names but incorrect.
  • The technique became foundational for bacterial classification.


Concept / Approach:
Hans Christian Gram, a Danish bacteriologist, developed the staining method while working with lung tissue sections to visualize bacteria. The method’s ability to differentiate bacteria based on cell wall characteristics led to its rapid adoption and lasting impact on clinical diagnostics.


Step-by-Step Solution:
Link the year 1884 with the Gram stain origin. Identify the correct full name: Hans Christian Gram. Eliminate other famous scientists not connected to this discovery.


Verification / Alternative check:
Historical articles and textbooks cite Gram’s original observations on differential retention of dyes after iodine and alcohol treatment.


Why Other Options Are Wrong:
Fleming discovered penicillin decades later; the other “Gram” names are distractors; Ehrlich contributed to staining and chemotherapy but not the Gram stain.


Common Pitfalls:
Confusing Gram with Ziehl or Ehrlich due to multiple eponymous stains in bacteriology.


Final Answer:
Hans Christian Gram.

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