Milestone in cloning In which year was Dolly, the first mammal cloned from an adult somatic cell, actually born?

Difficulty: Easy

Correct Answer: 1996

Explanation:


Introduction / Context:
Dolly the sheep is a landmark in biotechnology, demonstrating that a differentiated adult nucleus could be reprogrammed to totipotency via somatic cell nuclear transfer (SCNT).



Given Data / Assumptions:

  • The public announcement and publication occurred after the birth.
  • We need the actual birth year, not announcement year.


Concept / Approach:
Differentiate between the date of birth and the date of public disclosure. Dolly was born in mid-1996 and announced in 1997 after verification and peer review.



Step-by-Step Solution:

Recall SCNT steps: enucleate oocyte, insert donor nucleus, activate embryo, transfer to surrogate.Link to timeline: birth in 1996; Nature paper and media in 1997.


Verification / Alternative check:
Historical records from the Roslin Institute note Dolly’s birth on 5 July 1996.



Why Other Options Are Wrong:

  • 1997: announcement year, not birth.
  • 1995, 1998, 2000: do not match documented chronology.


Common Pitfalls:
Confusing publication year with the actual event date, common in science history questions.



Final Answer:
1996

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