Enhancing embryo numbers for transplantation The success of embryo transfer depends on obtaining many embryos from elite animals. Which intervention is specifically used to achieve this?

Difficulty: Easy

Correct Answer: FSH (Follicle Stimulating Hormone) for superovulation protocols

Explanation:


Introduction / Context:
Embryo transfer programs rely on superovulation to collect multiple embryos per cycle from genetically superior donors. The hormonal choice and regimen directly influence embryo yield and quality.



Given Data / Assumptions:

  • Goal is increased ovulation rate in the donor female.
  • Veterinary reproductive management and synchronization are available.


Concept / Approach:
FSH is the standard pituitary-derived (or recombinant) hormone administered in decreasing doses over several days to recruit and mature multiple follicles, markedly increasing ovulation numbers relative to natural cycles.



Step-by-Step Solution:

Select an exogenous hormone: FSH is preferred for multi-follicular recruitment.Administer according to a superovulation protocol aligned with estrous synchronization.Breed and recover embryos by uterine flushing on the appropriate day.


Verification / Alternative check:
Controlled studies show FSH regimens yield more transferable embryos than reliance on endogenous hormones alone.



Why Other Options Are Wrong:

  • Exogenous gonadotrophins (generic) are conceptually correct, but the specific, widely used agent is FSH; option (d) names it precisely.
  • Endogenous pulses: insufficient for superovulatory responses.
  • “Both without timing control”: timing is essential; lack of control reduces success.
  • Diet alone cannot induce superovulation.


Common Pitfalls:
Incorrect dosing schedules, poor synchronization, and ignoring donor variability (breed, parity) can lower embryo yields.



Final Answer:
FSH (Follicle Stimulating Hormone) for superovulation protocols

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