Enhancing embryo numbers for transplantation The success of embryo transfer depends on obtaining many embryos from elite animals. Which intervention is specifically used to achieve this?

Biotechnology Animal Breeding and Transgenic Animal Difficulty: Easy
Choose an option
  • A
    Exogenous gonadotrophic hormones (superovulation)
  • B
    Endogenous gonadotrophic pulses only
  • C
    Both exogenous and endogenous hormones without timing control
  • D
    FSH (Follicle Stimulating Hormone) for superovulation protocols
  • E
    Feeding high-energy diets only

Answer

Correct Answer: FSH (Follicle Stimulating Hormone) for superovulation protocols

Explanation

Introduction / Context:Embryo transfer programs rely on superovulation to collect multiple embryos per cycle from genetically superior donors. The hormonal choice and regimen directly influence embryo yield and quality.

Given Data / Assumptions:

  • Goal is increased ovulation rate in the donor female.
  • Veterinary reproductive management and synchronization are available.

Concept / Approach:FSH is the standard pituitary-derived (or recombinant) hormone administered in decreasing doses over several days to recruit and mature multiple follicles, markedly increasing ovulation numbers relative to natural cycles.

Step-by-Step Solution:

Select an exogenous hormone: FSH is preferred for multi-follicular recruitment.Administer according to a superovulation protocol aligned with estrous synchronization.Breed and recover embryos by uterine flushing on the appropriate day.

Verification / Alternative check:Controlled studies show FSH regimens yield more transferable embryos than reliance on endogenous hormones alone.

Why Other Options Are Wrong:

  • Exogenous gonadotrophins (generic) are conceptually correct, but the specific, widely used agent is FSH; option (d) names it precisely.
  • Endogenous pulses: insufficient for superovulatory responses.
  • “Both without timing control”: timing is essential; lack of control reduces success.
  • Diet alone cannot induce superovulation.

Common Pitfalls:Incorrect dosing schedules, poor synchronization, and ignoring donor variability (breed, parity) can lower embryo yields.

Final Answer:FSH (Follicle Stimulating Hormone) for superovulation protocols

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