Phage–host interactions — When a virus enters a cell but does not replicate immediately, what is this non-productive state called?

Microbiology Viruses Difficulty: Easy
Choose an option
  • A
    Lysogeny
  • B
    Fermentation
  • C
    Symbiosis
  • D
    Synergism

Answer

Correct Answer: Lysogeny

Explanation

Introduction / Context:Temperate bacteriophages can enter a dormant relationship with the host instead of immediately replicating and lysing the cell. Recognizing this state is essential for understanding bacterial virulence conversion, phage therapy, and prophage dynamics.

Given Data / Assumptions:

  • Virus enters cell and does not immediately replicate.
  • Context fits classic temperate phage behavior.
  • For animal viruses the analogous concept is latency, but in bacteriophages it is lysogeny.

Concept / Approach:Lysogeny occurs when phage DNA integrates into (or persists in) the bacterial chromosome as a prophage, maintained by repressor proteins that silence lytic genes. The host replicates the prophage passively during cell division, conferring immunity to superinfection by the same phage type.

Step-by-Step Solution:

Interpret “no immediate replication” as repression of lytic functions.Map this to the prophage state termed lysogeny.Exclude unrelated biological terms (fermentation, symbiosis, synergism).

Verification / Alternative check:Lambda phage models unequivocally define lysogeny as the nonproductive prophage state that can later switch (induce) to lysis.

Why Other Options Are Wrong:

  • Fermentation: microbial metabolism, not a viral lifecycle state.
  • Symbiosis: broad ecological term, lacks genetic control implications.
  • Synergism: interaction effect term, not a lifecycle state.

Common Pitfalls:Confusing lysogeny (phages) with latency (animal viruses); both are dormancy but in different biological contexts.

Final Answer:Lysogeny

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