ABO blood group compatibility: Considering the ABO system (with Rh compatibility assumed), type A blood can be donated to which recipient type?

Biochemistry Anti Bodies Difficulty: Easy
Choose an option
  • A
    Type AB individuals
  • B
    Type B individuals
  • C
    Contains type B antigens on red cells (statement about A blood)
  • D
    Can always be used for any Rh+ individual
  • E
    Type O individuals

Answer

Correct Answer: Type AB individuals

Explanation

Introduction / Context: Safe transfusion requires matching donor red cell antigens to recipient antibodies. In the ABO system, type A red cells express A antigen and will react with anti-A antibodies present in type B or type O recipients.

Given Data / Assumptions:

  • ABO compatibility only; Rh factor compatibility is assumed or separately matched.
  • Type A donor has A antigen on red cells and anti-B antibody in plasma.

Concept / Approach: Recipients with AB blood express both A and B antigens and have no anti-A or anti-B antibodies; therefore, they can receive A, B, AB, or O red cells (universal recipient for ABO). Type B recipients have anti-A, so A cells would be hemolyzed.

Step-by-Step Solution: Determine antigen/antibody profile: A cells carry A antigen. Identify compatible recipients lacking anti-A → AB (and A). Among listed choices, AB is broadly correct. Exclude misleading statements about Rh and incorrect antigen claims.

Verification / Alternative check: Crossmatching and ABO charts confirm A → A or AB, O → all types, AB → AB only (for red cells).

Why Other Options Are Wrong: Type B recipients have anti-A; saying A blood has B antigens is false; Rh+ statement ignores ABO incompatibility; O recipients would react to A antigen.

Common Pitfalls: Confusing plasma compatibility with red cell compatibility; ignoring Rh as a separate issue.

Final Answer: Type AB individuals.

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