Selective permeability of the plasma membrane The barrier properties of the plasma membrane depend primarily on the presence of which feature?

Difficulty: Easy

Correct Answer: Specific transport proteins

Explanation:


Introduction / Context:
Cells must regulate what enters and leaves. The lipid bilayer provides a hydrophobic barrier, but selectivity and controlled rates come from protein transport systems embedded in the membrane.



Given Data / Assumptions:

  • Lipids form a barrier to polar and charged solutes.
  • Transport proteins allow regulated passage of ions and molecules.
  • Carbohydrates are involved mainly in recognition, not translocation.



Concept / Approach:
Selective permeability emerges from channels, carriers, and pumps—each an integral protein with substrate specificity and gating/regulatory features. This contrasts with nonselective diffusion of hydrophobic solutes through lipids.



Step-by-Step Solution:
Identify the need: selectivity and regulation.Associate with mechanism: specific transport proteins (ion channels, uniporters, symporters, antiporters, ATPases).Eliminate options lacking transmembrane transport capabilities.



Verification / Alternative check:
Patch-clamp and transporter kinetics demonstrate substrate-specific conductance and saturable transport, respectively.



Why Other Options Are Wrong:

  • Amino acids / DNA: Not structural transport elements.
  • Carbohydrates: Key for cell–cell recognition but not for solute translocation.



Common Pitfalls:
Assuming the lipid bilayer alone confers selectivity; it mainly restricts polar solutes without specificity.



Final Answer:
Specific transport proteins.


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