Selective permeability of the plasma membrane The barrier properties of the plasma membrane depend primarily on the presence of which feature?
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ASpecific transport proteins
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BFree amino acids embedded in the bilayer
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CCarbohydrates alone on the outer leaflet
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DNone of these
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EDNA threads attached to the cytosolic face
Answer
Correct Answer: Specific transport proteins
Explanation
Introduction / Context:Cells must regulate what enters and leaves. The lipid bilayer provides a hydrophobic barrier, but selectivity and controlled rates come from protein transport systems embedded in the membrane.
Given Data / Assumptions:
- Lipids form a barrier to polar and charged solutes.
- Transport proteins allow regulated passage of ions and molecules.
- Carbohydrates are involved mainly in recognition, not translocation.
Concept / Approach:Selective permeability emerges from channels, carriers, and pumps—each an integral protein with substrate specificity and gating/regulatory features. This contrasts with nonselective diffusion of hydrophobic solutes through lipids.
Step-by-Step Solution:Identify the need: selectivity and regulation.Associate with mechanism: specific transport proteins (ion channels, uniporters, symporters, antiporters, ATPases).Eliminate options lacking transmembrane transport capabilities.
Verification / Alternative check:Patch-clamp and transporter kinetics demonstrate substrate-specific conductance and saturable transport, respectively.
Why Other Options Are Wrong:
- Amino acids / DNA: Not structural transport elements.
- Carbohydrates: Key for cell–cell recognition but not for solute translocation.
Common Pitfalls:Assuming the lipid bilayer alone confers selectivity; it mainly restricts polar solutes without specificity.
Final Answer:Specific transport proteins.