Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

• ADP ribosylation of adenylate cyclase that stops production of cAMP
• ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
• cleavage of rRNA that results in disruption of ribosome function
• ADP ribosylation of guanylate cyclase that stimulates production of cGMP