In eukaryotic cells, which phases together constitute the full cell cycle framework within which DNA replication occurs?

Difficulty: Easy

Correct Answer: G1, S, G2 and M

Explanation:


Introduction / Context:
DNA replication is restricted to a defined window of the eukaryotic cell cycle, but understanding that window requires viewing the entire cycle framework that orchestrates growth, synthesis, checkpoint control, and division.


Given Data / Assumptions:

  • Interphase consists of G1, S, and G2.
  • M phase encompasses mitosis and cytokinesis.
  • DNA replication itself occurs during S phase.


Concept / Approach:
The complete canonical eukaryotic cell cycle is G1 (growth), S (DNA synthesis), G2 (preparation/checking), and M (mitosis). Many exam items ask for the set of phases constituting the cycle, not only the single phase where replication happens.


Step-by-Step Solution:

List all standard phases: G1, S, G2, M.Identify replication window: S phase.Select the option that includes the full framework (not a subset): G1, S, G2 and M.Confirm that other options omit necessary phases.


Verification / Alternative check:
Cell-cycle markers (cyclins/CDKs) and DNA content analysis (flow cytometry) define these stages, with 1C → 2C DNA increase in S phase.


Why Other Options Are Wrong:

  • G1, G2 and M: omits S phase.
  • S, G2 and M: omits G1.
  • G2 and M: incomplete.
  • S only: names the synthesis phase, not the whole cycle.


Common Pitfalls:
Answering “S phase” when the question asks for the cell-cycle composition rather than the replication window.


Final Answer:
G1, S, G2 and M

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