For aerated mixing vessels in an aqueous solution, the mass transfer coefficient (kL) co-relating power consumption (Pm) and fermenter volume (V) can be expressed as
Options
A. kL ? (Pm/V)0.33
B. kL ? (Pm/V)0.66
C. kL ? (Pm/V)0.50
D. kL ? (Pm/V)
Correct Answer
kL ? (Pm/V)0.33
Agitation and Aeration problems
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1. Flooding is a condition/phenomenon which occur in a bioreactor when
Options
A. The air escapes without being distributed by the agitator
B. The fermenter medium spills out the reactor due to foaming
C. The volume of foam is more than the volume of broth
Correct Answer: Off-centre impellers should only be used with reactors with volumes less than 10 m3
3. A cylindrical reactor fitted with Rushton Turbine has a liquid volume of 100,000 litres. It has an aspect ratio (the ratio of the channel height to the width) of 2:1. The diameter of the impeller should be approximately:
7. A fermentation system has a KLa of 3 s-1 and a C0* of 5 ppm of O2. If the bulk liquid is completely depleted of oxygen, then the oxygen transfer rate will be equal to
Correct Answer: they provide high shear mixing conditions
10. A fermentation system has a KLa of 3 s-1 and a C0* of 5 ppm of O2. If the bulk liquid is saturated with oxygen then the oxygen transfer rate will be equal to