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Home Biochemical Engineering Downstream Processing Comments

  • Question
  • Maintenance cost varies from


  • Options
  • A. 0-4% of the capital cost
  • B. 12-16% of the capital cost
  • C. 4-8% of the capital cost
  • D. 8-12% of the capital cost

  • Correct Answer
  • 4-8% of the capital cost 


  • Downstream Processing problems


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    • 1. A common filter medium is the cloth filter generally made of

    • Options
    • A. canvas
    • B. synthetic fabrics
    • C. metal or glass fiber
    • D. all of these
    • Discuss
    • 2. Chromatography is based on the

    • Options
    • A. different rate of movement of the solute in the column
    • B. separation of one solute from other constituents by being captured on the adsorbent
    • C. different rate of movement of the solvent in the column
    • D. any of the above
    • Discuss
    • 3. In antibiotic manufacturing processes, the fermentation time ranges from

    • Options
    • A. 2-3 weeks
    • B. 1-2 weeks
    • C. 4-5 weeks
    • D. 2-4 weeks
    • Discuss
    • 4. Which of the following can act as a shear protectorant?

    • Options
    • A. Serum
    • B. Silicone oil
    • C. Glucose
    • D. Glutamic acid
    • Discuss
    • 5. A stirred tank reactor containing a fluid with a density of 2.5 g.ml-1 and viscosity of 0.002 kg m-1s-1 is mixed at 120 rpm. If the fluid is mixed with an impeller having diameter 50 cm, then the Reynolds number of the liquid in the reactor is

    • Options
    • A. 2500
    • B. 100
    • C. 12,50,000
    • D. 1,000,000
    • Discuss
    • 6. The stage wise operation of adsorption is called

    • Options
    • A. contact filtration
    • B. conventional adsorption
    • C. affinity adsorption
    • D. ion exchange
    • Discuss
    • 7. The purity of a solute collected between two times t1 and t2 during chromatographic separation can be calculated as

    • Options
    • A. amount of solute eluted - amount of impurity eluted
    • B. amount of solute eluted / amount of impurity eluted
    • C. amount of solvent eluted + amount of impurity eluted
    • D. amount of solvent eluted / amount of impurity eluted
    • Discuss
    • 8. Start up expenses in a fermentation industry varies from

    • Options
    • A. 0-5% of the capital cost
    • B. 10-15% of the capital cost
    • C. 5-10% of the capital cost
    • D. 15-20% of the capital cost
    • Discuss
    • 9. Selectivity can be expressed as

    • Options
    • A. ratio of the distribution coefficients in different solute
    • B. mass fraction of the solute in the extract phase at equilibrium
    • C. mass fraction of the solute in the raffinate phase
    • D. ratio of the mass fraction of the solute in the extract phase to the raffinate phase
    • Discuss
    • 10. Concentration polarization can be reduced further by

    • Options
    • A. pre filtering the solution
    • B. reducing the flow rate per unit membrane surface area
    • C. back washing periodically
    • D. all of the above
    • Discuss


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