Mixing and mass transfer hardware in a stirred-tank fermentor Which components contribute to agitation and effective gas–liquid mass transfer inside a typical aerobic fermentor?
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AImpeller (agitator) to impart bulk mixing and shear
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BBaffles to suppress vortexing and enhance turbulence
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CSparger to introduce gas bubbles and aid dispersion
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DAll of these
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ESight glass (viewing port) for optical inspection
Answer
Correct Answer: All of these
Explanation
Introduction / Context:Efficient aerobic fermentation requires thorough mixing and high oxygen transfer rates. Vessel internals are designed to work together to achieve target kLa and homogeneous conditions.
Given Data / Assumptions:
- Standard stirred-tank design with top- or bottom-driven impellers.
- Presence of baffles and a gas sparger typical for aerobic runs.
Concept / Approach:The impeller provides mechanical energy, generating circulation loops and break-up of gas bubbles. Baffles disrupt swirl, increasing turbulence and preventing vortex formation. The sparger introduces gas that is then dispersed into fine bubbles by the impeller, increasing interfacial area.
Step-by-Step Solution:
Relate each component to its function: impeller (mixing), baffles (flow pattern control), sparger (gas introduction).Recognize synergy: impeller and baffles together maximize bubble dispersion and oxygen transfer.Conclude that all listed components contribute to agitation and mass transfer performance.Verification / Alternative check:Design manuals quantify kLa as a function of power input, gas flow, and internals configuration—demonstrating the combined roles.
Why Other Options Are Wrong:
- Sight glass: useful operationally but does not create agitation or mass transfer.
Common Pitfalls:Assuming the sparger alone ensures mixing; under-baffled tanks suffer vortexing and poor gas dispersion.
Final Answer:All of these