Endocrinology fundamentals — identify the catecholamine among the following hormones.
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AFollitropin (FSH)
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BNorepinephrine
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CTetraiodothyronine (thyroxine, T4)
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DTetrahydrofolate
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EAldosterone
Answer
Correct Answer: Norepinephrine
Explanation
Introduction / Context:Catecholamines are tyrosine-derived neurotransmitters/hormones (dopamine, norepinephrine, epinephrine) containing a catechol ring. Distinguishing them from peptide and steroid/iodothyronine hormones is a core classification skill.
Given Data / Assumptions:
- Norepinephrine is synthesized from dopamine via dopamine β-hydroxylase.
- FSH is a glycoprotein peptide hormone.
- Thyroxine (T4) is an iodinated amino acid derivative, but not a catecholamine.
- Tetrahydrofolate is a coenzyme, not a hormone.
Concept / Approach:Identify the only option with a catechol nucleus (benzene ring with two adjacent hydroxyls) and known adrenergic activity.
Step-by-Step Solution:Scan options for classical catecholamine names.Confirm norepinephrine as a sympathetic neurotransmitter/hormone.Eliminate peptide, iodothyronine, and cofactor choices.Select “Norepinephrine.”
Verification / Alternative check:Physiology texts list norepinephrine as a primary catecholamine alongside epinephrine and dopamine.
Why Other Options Are Wrong:FSH is peptidic; T4 lacks catechol structure; tetrahydrofolate is a vitamin cofactor.
Common Pitfalls:Assuming all amino acid–derived hormones are catecholamines; iodothyronines are distinct.
Final Answer:Norepinephrine.