Difficulty: Easy
Correct Answer: Fluoride ion
Explanation:
Introduction / Context:
Dental caries resistance is influenced by enamel composition. Fluoride incorporation into hydroxyapatite forms fluorapatite, which is less soluble in acid and more resistant to demineralization during bacterial fermentation in dental plaque. Public health programs leverage this chemistry to prevent decay.
Given Data / Assumptions:
Concept / Approach:
Fluoride promotes remineralization and inhibits demineralization. It can also reduce bacterial acid production by inhibiting enolase in glycolysis at higher local concentrations. The net effect is fewer and shallower lesions over time, particularly when exposure occurs during enamel maturation and via daily topical contact.
Step-by-Step Solution:
Verification / Alternative check:
Epidemiological studies show lower caries prevalence with optimally fluoridated water and fluoride toothpaste use, confirming the protective mechanism.
Why Other Options Are Wrong:
Common Pitfalls:
Assuming more fluoride is always better; excess leads to fluorosis. The benefit hinges on appropriate dosing.
Final Answer:
Fluoride ion
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