Which of the following hepatitis viruses is NOT an RNA virus? (Identify the DNA virus among common hepatitis agents.)

Difficulty: Easy

Correct Answer: Hepatitis B virus

Explanation:


Introduction:
Most hepatitis viruses are RNA viruses, but one major exception exists. This question tests recognition of the unique nucleic acid type that distinguishes hepatitis B virus (HBV) from other hepatitis agents.


Given Data / Assumptions:

  • HAV, HEV, and HGV (GB virus C) are RNA viruses.
  • HBV belongs to the Hepadnaviridae family and possesses DNA.
  • Classification is based on genome type, not clinical syndrome severity.


Concept / Approach:
HBV contains a partially double-stranded, circular DNA genome and replicates via reverse transcription. In contrast, HAV (Picornaviridae), HEV (Hepeviridae), and HGV/GBV-C (Flaviviridae-related) carry single-stranded RNA genomes.


Step-by-Step Solution:
List genome types for each candidate. Single out the DNA-containing virus (HBV). Confirm others are RNA viruses. Choose the only non-RNA option.


Verification / Alternative check:
Standard virology references classify HBV as a DNA virus with reverse transcriptase activity.


Why Other Options Are Wrong:

  • Hepatitis A / E / G: All are RNA viruses.


Common Pitfalls:
Confusing replication via reverse transcriptase (seen in HBV) with RNA genome possession; HBV is still a DNA virus.


Final Answer:
Hepatitis B virus is not an RNA virus.

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