Rabies virology: What is the characteristic morphology (shape) of the rabies virus particle?

Difficulty: Easy

Correct Answer: Bullet-shaped

Explanation:


Introduction / Context:
Rabies virus, a member of the Rhabdoviridae family (genus Lyssavirus), displays a unique virion morphology that is a favorite viva and MCQ point in microbiology and pathology exams. Recognizing its classic shape helps link clinical suspicion to lab and imaging descriptions.


Given Data / Assumptions:

  • Organism: Rabies virus (enveloped, negative-sense RNA).
  • Question: Identify the canonical virion shape.
  • Answer should reflect standard textbook morphology.


Concept / Approach:
Rhabdoviruses are famously “bullet-shaped” on electron microscopy, with one rounded end and one flattened end, a helical nucleocapsid, and an envelope studded with glycoprotein spikes. This contrasts with the roughly spherical shape of many orthomyxoviruses and coronaviruses.


Step-by-Step Solution:
Recall family hallmark: Rhabdoviridae → bullet-shaped virions. Differentiate from common distractors (spherical, filamentous). Choose the textbook descriptor: bullet-shaped.


Verification / Alternative check:
Electron micrographs and standard references consistently describe rabies virions as bullet-like with a helical ribonucleoprotein core.


Why Other Options Are Wrong:
Spherical/polygonal/tubular/filamentous forms better fit other viral families; they do not capture rabies morphology.


Common Pitfalls:
Confusing “helical symmetry” of the nucleocapsid with overall particle shape; for rabies, the envelope gives the distinctive bullet outline.


Final Answer:
Bullet-shaped.

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