Mitochondrial and chloroplast codes: In some eukaryotic organelles, how does the genetic code compare to the standard bacterial code?

Difficulty: Easy

Correct Answer: It differs from that used in prokaryotes

Explanation:


Introduction / Context:
The genetic code is nearly universal, but notable exceptions occur in organelles such as mitochondria (and some chloroplasts). Recognizing these deviations is important in genomics and interpreting organelle-encoded proteins.



Given Data / Assumptions:

  • Certain mitochondrial genomes reassign codons (e.g., UGA as tryptophan in human mitochondria).
  • Start and stop assignments may differ.
  • Question asks if organelle codes differ from prokaryotic standard.


Concept / Approach:
Organelle translation systems evolved specialized tRNAs and factors, leading to codon reassignments. Hence, their codes differ from the canonical bacterial code, even though many codons are the same.



Step-by-Step Solution:

Recall examples of codon reassignment (e.g., AUA as methionine in mitochondria).Note that “nearly universal” allows exceptions.Select the option indicating difference from prokaryotes.


Verification / Alternative check:
Translation tables (e.g., NCBI genetic codes) list multiple alternative codes for mitochondria and some nuclear lineages.



Why Other Options Are Wrong:

  • Exactly the same: contradicted by known reassignments.
  • Partially the same but identical: internally inconsistent.
  • None: a clear, accurate statement exists.


Common Pitfalls:
Assuming “universal” means no exceptions; in practice, exceptions are critical in sequence annotation.



Final Answer:
It differs from that used in prokaryotes

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