Difficulty: Easy
Correct Answer: They provide high-shear, highly turbulent mixing that enhances gas dispersion
Explanation:
Introduction / Context:
Choosing the right impeller for aerobic fermentation is central to achieving adequate oxygen transfer. Radial-flow impellers such as the Rushton turbine are classics in bioprocessing because they generate intense local turbulence and strong gas dispersion, raising interfacial area and kLa under many conditions.
Given Data / Assumptions:
Concept / Approach:
Radial-flow turbines discharge flow laterally into baffles, creating high energy dissipation zones. The resulting shear breaks bubbles into smaller sizes, increasing interfacial area and improving dispersion uniformity, which typically elevates kLa compared to gentle, low-shear devices.
Step-by-Step Solution:
Verification / Alternative check:
kLa correlations often show higher exponents on power input for Rushton turbines versus some axial designs in particular regimes, corroborating their dispersion strength.
Why Other Options Are Wrong:
Common Pitfalls:
Assuming high shear is always beneficial; for shear-sensitive cells, axial-flow alternatives may be preferable.
Final Answer:
They provide high-shear, highly turbulent mixing that enhances gas dispersion
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