Difficulty: Easy
Correct Answer: covalently bonded
Explanation:
Introduction / Context:
Precise terminology—nucleoside versus nucleotide—is foundational in biochemistry. Mislabeling can cause confusion in pathways like salvage, phosphorylation, and nucleic acid synthesis.
Given Data / Assumptions:
Concept / Approach:
A nucleoside has a nitrogenous base linked to a pentose sugar via a covalent N-glycosidic bond (N9 of purines or N1 of pyrimidines to C1' of the sugar). Ionic or hydrogen bonds do not define the core nucleoside linkage.
Step-by-Step Solution:
Identify components: base + sugar.Recall linkage: N-glycosidic covalent bond.Therefore, “covalently bonded” is correct.
Verification / Alternative check:
Hydrolysis under acidic conditions cleaves the glycosidic bond—consistent with a covalent linkage.
Why Other Options Are Wrong:
Common Pitfalls:
Confusing nucleosides with nucleotides (which include phosphate).
Final Answer:
covalently bonded
Discussion & Comments