Minimum criteria for a microarray device To qualify as a microarray, the analytical device must satisfy which set of attributes?

Difficulty: Easy

Correct Answer: All of these (ordered, microscopic, planar, and specific)

Explanation:


Introduction / Context:
Microarrays rely on many miniature test sites arranged in an ordered pattern on a planar support, enabling simultaneous specific binding events and readout.



Given Data / Assumptions:

  • “Micro” implies microscopic feature size.
  • Arrays require an ordered layout to map signals to probes.
  • Planar substrates (glass, silicon) are standard.
  • Specific recognition is essential for meaningful analytics.


Concept / Approach:
All listed attributes—order, micro-scale features, planar geometry, and specificity—are fundamental. Lacking any one compromises the definition or utility of a microarray device.



Step-by-Step Solution:

Assess each attribute relative to core definitions.Recognize that “all of these” correctly bundles the minimal criteria.


Verification / Alternative check:
Manufacturers and standards documents specify planar substrates with ordered spots of micrometer scale and validated specific binding chemistries.



Why Other Options Are Wrong:

  • Single-attribute choices are incomplete.
  • Fluorescence detection is common but not definitional; label-free arrays exist.


Common Pitfalls:
Equating detection method with platform definition; the geometry and specificity define microarrays.



Final Answer:
All of these (ordered, microscopic, planar, and specific)

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