By which of the following means antifungal chemotherapeutic agents may affect fungi?

• Interfere with nuclear division by preventing the aggregation of microtubules needed for mitosis
• Interfere with normal nucleic acid synthesis
• Interfere with ergosterol biosynthesis and thus alter the structure of the cytoplasmic membrane as well as the function of several membrane-bound enzymes like those involved in nutrient transport and chitin synthesis
• all of these