What is the ideal tubular-flow fermenter model (no radial gradients, no axial mixing) commonly called in biochemical engineering?
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APlug flow fermenter
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BContinuous stirred tank fermenter (CSTF)
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CColumn fermenter (unspecified hydraulics)
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DHigh-dilution fermenter at the washout point
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EBatch bubble column
Answer
Correct Answer: Plug flow fermenter
Explanation
Introduction / Context:Fermenter hydrodynamics are frequently idealized as either perfectly mixed tanks or plug flow tubes. The chosen model affects predicted conversions, selectivities, and scale-up strategies.
Given Data / Assumptions:
- Tubular flow without radial gradients.
- Negligible axial dispersion (no backmixing).
- Steady operation.
Concept / Approach:These assumptions define a plug flow device. In biochemical engineering contexts, the term “plug flow fermenter” mirrors the chemical engineering “PFR” and is contrasted with the “CSTR” (continuous stirred tank fermenter).
Step-by-Step Solution:
Match hydrodynamic assumptions to canonical models.No radial gradients + no axial mixing → plug flow.Therefore, the ideal tubular-flow fermenter is called a plug flow fermenter.Other names (column fermenter) do not guarantee plug hydrodynamics.Verification / Alternative check:Residence-time distribution tests for an ideal PFR yield a narrow distribution; CSTRs show exponential RTD, confirming model differences.
Why Other Options Are Wrong:
- CSTF: represents perfect mixing, not plug flow.
- Column fermenter: geometry only; flow may be mixed or dispersed.
- High-dilution/washout: an operating condition, not a hydrodynamic model.
- Batch bubble column: unsteady, gas–liquid mixing; not plug flow by default.
Common Pitfalls:Equating vessel geometry with hydrodynamics; true plug flow is a kinetic idealization, not guaranteed by a cylindrical shape.
Final Answer:Plug flow fermenter