During transcription in gene expression, which of the following events takes place inside the cell?

Difficulty: Easy

Correct Answer: Genetic information in DNA is copied into a complementary RNA molecule.

Explanation:


Introduction / Context:
Gene expression involves two main steps: transcription and translation. Each step has a specific role and occurs in different parts of the cell. Examinations often test whether students can correctly distinguish what happens at each step. This question asks you to identify what specifically occurs during transcription, not translation or other processes.



Given Data / Assumptions:

  • We are focusing on the process called transcription.
  • Options mention protein production, ribosome activity, copying of DNA information into RNA, and copying RNA back into DNA.
  • We assume knowledge of the central dogma: DNA to RNA to protein.
  • Only one of the listed events correctly describes transcription.


Concept / Approach:
Transcription is the process by which the sequence of bases in DNA is used to synthesize a complementary RNA molecule, usually messenger RNA (mRNA). RNA polymerase binds to a DNA template and builds an RNA transcript using base pairing rules. Translation is the subsequent step in which ribosomes use the mRNA sequence to assemble amino acids into a polypeptide. Copying RNA information back into DNA (reverse transcription) occurs in some viruses and laboratory techniques but is not part of normal transcription in cells. Therefore, the correct description of transcription is copying genetic information from DNA into RNA.



Step-by-Step Solution:
Step 1: Recall the central dogma: DNA is transcribed into RNA, and RNA is translated into protein. Step 2: Identify transcription as the step where RNA polymerase creates an RNA strand from a DNA template. Step 3: Recognise that protein production, or synthesis of polypeptides from mRNA, occurs in translation, not during transcription. Step 4: Understand that ribosome assembly and their movement along mRNA are features of translation, not transcription. Step 5: Note that copying RNA back into DNA is reverse transcription, not standard transcription in most cells. Step 6: Conclude that the event describing DNA information being copied into RNA is the correct description of transcription.


Verification / Alternative check:
Molecular biology textbooks define transcription as the synthesis of an RNA molecule from a DNA template, catalysed by RNA polymerase. They highlight transcription steps: initiation, elongation, and termination, all related to building an RNA transcript. Separate sections then describe translation as the process where ribosomes read mRNA and synthesize proteins. Reverse transcription is discussed mainly in the context of retroviruses and specialised laboratory enzymes like reverse transcriptase, not as normal cellular transcription. This confirms that copying DNA information to RNA is the correct answer.



Why Other Options Are Wrong:
Proteins are produced directly from the mRNA code: This describes translation, not transcription. Ribosomes are assembled and begin translating amino acid chains: Again, this is part of translation and ribosome function, not transcription. All of the above events occur during transcription: Incorrect because only one of the listed events, copying DNA to RNA, is actually transcription. RNA information is copied back into a new DNA strand: This is reverse transcription, which is not standard cellular transcription in most organisms.


Common Pitfalls:
Students often confuse transcription and translation because both are part of gene expression and involve RNA. Another pitfall is thinking that transcription includes all steps from DNA to protein. To avoid confusion, remember that transcription stops once an RNA molecule is produced; translation is a separate step where proteins are synthesized. Also, keep in mind that reverse transcription is a special case, not the normal definition of transcription.



Final Answer:
During transcription, genetic information in DNA is copied into a complementary RNA molecule.

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