Difficulty: Easy
Correct Answer: Replication (DNA-directed DNA synthesis)
Explanation:
Introduction / Context:
Central dogma steps—replication, transcription, and translation—have distinct information flows. Only one process duplicates the genetic material itself to pass to daughter cells: replication.
Given Data / Assumptions:
Concept / Approach:
Replication is semi-conservative: each daughter duplex contains one parental and one newly synthesized strand. DNA polymerases copy templates in the 5′→3′ direction using primers. Transcription produces RNA, translation produces polypeptides, transformation and recombination alter DNA content but do not copy the entire DNA molecule as a dedicated process.
Step-by-Step Solution:
Define “exact new copy” as duplication of the DNA duplex.Identify the enzymatic process that accomplishes this: DNA replication.Exclude transcription (DNA→RNA), translation (RNA→protein), and transformation/recombination (DNA movement/reshuffling).
Verification / Alternative check:
Meselson–Stahl experiments demonstrated semi-conservative replication using isotope labeling of DNA strands, directly confirming the mechanism.
Why Other Options Are Wrong:
Common Pitfalls:
Equating “trans” words (transcription/translation/transformation) with duplication; only replication duplicates DNA.
Final Answer:
Replication (DNA-directed DNA synthesis)
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