Pharmaceuticals: which of the following is a drug used in oral contraceptive formulations (as an estrogen component)?
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AMestranol
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BPenicillin
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CMethyl salicylate
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DSulphadiazine
Answer
Correct Answer: Mestranol
Explanation
Introduction:Combined oral contraceptives typically contain an estrogen and a progestin. Recognizing common active ingredients is important for pharmacy, medicine, and biotechnology students.
Given Data / Assumptions:
- Mestranol is a synthetic estrogen (a prodrug of ethinyl estradiol).
- Other listed compounds have unrelated indications.
- Question asks specifically for a contraceptive drug.
Concept / Approach:Estrogen components (e.g., mestranol, ethinyl estradiol) are combined with progestins (e.g., norethindrone, levonorgestrel) to suppress ovulation and alter the endometrium/cervical mucus. Antibiotics (penicillin), analgesic/liniment component (methyl salicylate), and antibacterial sulfonamide (sulphadiazine) are not used as contraceptives.
Step-by-Step Solution:Identify estrogenic agent: mestranol.Exclude antibiotics/analgesics: not contraceptives.Select mestranol as correct contraceptive component.
Verification / Alternative check:Drug compendia list mestranol–norethindrone as a historical combination; modern products often use ethinyl estradiol instead of mestranol but the classification remains valid.
Why Other Options Are Wrong:
- Penicillin: antimicrobial, no contraceptive effect.
- Methyl salicylate: topical counterirritant.
- Sulphadiazine: antibacterial sulfonamide.
Common Pitfalls:Assuming any hormone-like name is a contraceptive; only specific estrogens/progestins are used for this indication.
Final Answer:Mestranol