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Home Biochemical Engineering Downstream Processing Comments

  • Question
  • For the extractions operation, the selectivity should be


  • Options
  • A. > 1
  • B. < 1
  • C. 1
  • D. zero

  • Correct Answer
  • > 1 


  • Downstream Processing problems


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    • 1. For cost analysis in a fermentor system, the depreciation cost varies from

    • Options
    • A. 5-6% of the capital cost
    • B. 6-7% of the capital cost
    • C. 6-10% of the capital cost
    • D. 8-10% of the capital cost
    • Discuss
    • 2. An ion exchange resin is composed of

    • Options
    • A. polymeric network
    • B. ionic functional groups
    • C. counter ions
    • D. all of these
    • Discuss
    • 3. Which of the operation does not come under upstream processing?

    • Options
    • A. Media preparation
    • B. Inoculum development
    • C. Effluent treatment
    • D. Storage of raw material
    • Discuss
    • 4. Filtration leaf test results indicate that the filtration rate of a protein product is 100 dry lbs/(ft2 hr). What size production filter would be required to obtain 100 dry lbs of filter cake/hr?

    • Options
    • A. 1.54 ft2
    • B. 3.08 ft2
    • C. 65 ft2
    • D. 65 lbs/ ft2.hr
    • Discuss
    • 5. Assuming the laminar flow across the filter, the rate of filtration (dVf/dt) can be expressed as a function of pressure drop Dp by the modified D'Arcy's equation as (where A is the area of filtering surface, K is the D'Arcy's filter cake permeability and L is the thickness of the filter cake)

    • Options
    • A. (1/A) dVf/dt = ?p/?(L/K)
    • B. dVf/dt = (1/A)?p/?(L/K)
    • C. (1/A) dVf/dt = ?p/? LK
    • D. dVf/dt = (1/A)?p/? LK
    • Discuss
    • 6. The efficiency of cell disruption in a bead mill depends on the

    • Options
    • A. concentration of the cells
    • B. amount and size of beads
    • C. type and rotational speed of agitation
    • D. all of these
    • Discuss
    • 7. Conventional adsorption is a

    • Options
    • A. reversible process
    • B. irreversible process
    • C. either reversible or irreversible
    • D. none of these
    • Discuss
    • 8. If the solute passes through membrane freely, the the rejection coefficient (s) is

    • Options
    • A. 1
    • B. 0
    • C. >1
    • D. <1
    • Discuss
    • 9. The conventional filtration involves the separation of large particles generally

    • Options
    • A. dp>5?m
    • B. dp>10?m
    • C. dp>15?m
    • D. dp>20?m
    • Discuss
    • 10. Micro filtration refers to the separation of suspended material such as bacteria by using a membrane with spore sizes of

    • Options
    • A. 0.02 to 10?m
    • B. 1-10A°
    • C. 20-30?m
    • D. 10-200A°
    • Discuss


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