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Biochemical Engineering
‣
Downstream Processing
Comments
Question
The purity of a solute collected between two times
t
1
and
t
2
during chromatographic separation can be calculated as
Options
A. amount of solute eluted - amount of impurity eluted
B. amount of solute eluted / amount of impurity eluted
C. amount of solvent eluted + amount of impurity eluted
D. amount of solvent eluted / amount of impurity eluted
Correct Answer
amount of solute eluted / amount of impurity eluted
Downstream Processing problems
Search Results
1. The stage wise operation of adsorption is called
Options
A. contact filtration
B. conventional adsorption
C. affinity adsorption
D. ion exchange
Show Answer
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Discuss
Correct Answer: contact filtration
2. Maintenance cost varies from
Options
A. 0-4% of the capital cost
B. 12-16% of the capital cost
C. 4-8% of the capital cost
D. 8-12% of the capital cost
Show Answer
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Discuss
Correct Answer: 4-8% of the capital cost
3. A common filter medium is the cloth filter generally made of
Options
A. canvas
B. synthetic fabrics
C. metal or glass fiber
D. all of these
Show Answer
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Discuss
Correct Answer: all of these
4. Chromatography is based on the
Options
A. different rate of movement of the solute in the column
B. separation of one solute from other constituents by being captured on the adsorbent
C. different rate of movement of the solvent in the column
D. any of the above
Show Answer
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Discuss
Correct Answer: different rate of movement of the solute in the column
5. In antibiotic manufacturing processes, the fermentation time ranges from
Options
A. 2-3 weeks
B. 1-2 weeks
C. 4-5 weeks
D. 2-4 weeks
Show Answer
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Correct Answer: 4-5 weeks
6. Start up expenses in a fermentation industry varies from
Options
A. 0-5% of the capital cost
B. 10-15% of the capital cost
C. 5-10% of the capital cost
D. 15-20% of the capital cost
Show Answer
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Correct Answer: 5-10% of the capital cost
7. Selectivity can be expressed as
Options
A. ratio of the distribution coefficients in different solute
B. mass fraction of the solute in the extract phase at equilibrium
C. mass fraction of the solute in the raffinate phase
D. ratio of the mass fraction of the solute in the extract phase to the raffinate phase
Show Answer
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Discuss
Correct Answer: ratio of the distribution coefficients in different solute
8. Concentration polarization can be reduced further by
Options
A. pre filtering the solution
B. reducing the flow rate per unit membrane surface area
C. back washing periodically
D. all of the above
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Correct Answer: all of the above
9. The solvent flux across the membrane can be expressed as (where
A
is the area,
L
p
is the membrane permeability, ? is the reflection point, ?
p
is applied pressure and ?? is the osmotic pressure)
Options
A.
J
=
L
p
(?
p
- ???)
B.
J/A
=
L
p
(?
p
- ???)
C.
J
=
L
p
/???
D.
J/A
=
L
p
/?
p
Show Answer
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Discuss
Correct Answer:
J
=
L
p
(?
p
- ???)
10. A typical tubular centrifuge has a bowl of 2 to 5 inch in diameter and 9 to 30 inch in height with a maximum rotating speed of
Options
A. 15,000 to 50,000 rpm
B. 50,000 to 100,000 rpm
C. 100,000 to 150,000 rpm
D. 150,000 to 200,000 rpm
Show Answer
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Correct Answer: 15,000 to 50,000 rpm
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