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Home Biochemical Engineering Downstream Processing Comments

  • Question
  • The stage wise operation of adsorption is called


  • Options
  • A. contact filtration
  • B. conventional adsorption
  • C. affinity adsorption
  • D. ion exchange

  • Correct Answer
  • contact filtration 


  • Downstream Processing problems


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    • 1. Maintenance cost varies from

    • Options
    • A. 0-4% of the capital cost
    • B. 12-16% of the capital cost
    • C. 4-8% of the capital cost
    • D. 8-12% of the capital cost
    • Discuss
    • 2. A common filter medium is the cloth filter generally made of

    • Options
    • A. canvas
    • B. synthetic fabrics
    • C. metal or glass fiber
    • D. all of these
    • Discuss
    • 3. Chromatography is based on the

    • Options
    • A. different rate of movement of the solute in the column
    • B. separation of one solute from other constituents by being captured on the adsorbent
    • C. different rate of movement of the solvent in the column
    • D. any of the above
    • Discuss
    • 4. In antibiotic manufacturing processes, the fermentation time ranges from

    • Options
    • A. 2-3 weeks
    • B. 1-2 weeks
    • C. 4-5 weeks
    • D. 2-4 weeks
    • Discuss
    • 5. Which of the following can act as a shear protectorant?

    • Options
    • A. Serum
    • B. Silicone oil
    • C. Glucose
    • D. Glutamic acid
    • Discuss
    • 6. The purity of a solute collected between two times t1 and t2 during chromatographic separation can be calculated as

    • Options
    • A. amount of solute eluted - amount of impurity eluted
    • B. amount of solute eluted / amount of impurity eluted
    • C. amount of solvent eluted + amount of impurity eluted
    • D. amount of solvent eluted / amount of impurity eluted
    • Discuss
    • 7. Start up expenses in a fermentation industry varies from

    • Options
    • A. 0-5% of the capital cost
    • B. 10-15% of the capital cost
    • C. 5-10% of the capital cost
    • D. 15-20% of the capital cost
    • Discuss
    • 8. Selectivity can be expressed as

    • Options
    • A. ratio of the distribution coefficients in different solute
    • B. mass fraction of the solute in the extract phase at equilibrium
    • C. mass fraction of the solute in the raffinate phase
    • D. ratio of the mass fraction of the solute in the extract phase to the raffinate phase
    • Discuss
    • 9. Concentration polarization can be reduced further by

    • Options
    • A. pre filtering the solution
    • B. reducing the flow rate per unit membrane surface area
    • C. back washing periodically
    • D. all of the above
    • Discuss
    • 10. The solvent flux across the membrane can be expressed as (where A is the area, Lp is the membrane permeability, ? is the reflection point, ?p is applied pressure and ?? is the osmotic pressure)

    • Options
    • A. J = Lp(?p - ???)
    • B. J/A = Lp(?p - ???)
    • C. J = Lp/???
    • D. J/A = Lp/?p
    • Discuss


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