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  • Question
  • Which of the following statements is most accurate regarding infection with parvovirus B19?


  • Options
  • A. Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors
  • B. Parvovirus B19 can cause hydrops fetalis via transplacental infection of a fetus in a seropositive mother
  • C. Parvovirus B19 can be diagnosed by detection of viral RNA using PCR or hybridization assays
  • D. Parvovirus B19 replicates in the host cell nucleus utilizing a virally encoded DNA polymerase to create a double- stranded DNA intermediate

  • Correct Answer
  • Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors 

    Explanation

    Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors.

     

    a. Parvovirus B19 binds preferentially to the erythrocyte blood group P antigen on erythroid precursor cells.

    Answers B, C, D are incorrect:

    b. after entry the single-stranded viral DNA genome is transported to the cell nucleus where the host DNA polymerase synthesizes the complimentary DNA strand.

    c. Parvovirus B19 infection can be diagnosed by direct detection of viral DNA not RNA.

    d. the fetus of a seropositive mother is protected from infection by maternal circulating antibodies.

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    More questions

    • 1. The term 'Caddle' is associates with which sports?

    • Options
    • A. Golf
    • B. Billiards
    • C. Polo
    • D. Bridge
    • Discuss
    • 2. Rectifiers are used to convert

    • Options
    • A. Direct current to Alternating current
    • B. Alternating current to Direct current
    • C. high voltage to low voltage
    • D. low voltage to high voltage
    • Discuss
    • 3. Main circuit board in a computer is...

    • Options
    • A. Decoder
    • B. Highlight
    • C. Select
    • D. Mother board
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    • 4. In which decade was the first solid state integrated circuit demonstrated?

    • Options
    • A. 1950s
    • B. 1960s
    • C. 1970s
    • D. 1980s
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    • 5. Which Indian batsman made three consecutive centuries in his first three Test matches?

    • Options
    • A. Vinoo Mankad
    • B. Mohd. Azaruddin
    • C. S.M. Gavaskar
    • D. G.R. Viswanath
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    • 6. Changing computer language of 1's and 0's to characters that a person can understand is...

    • Options
    • A. Highlight
    • B. Clip art
    • C. Decode
    • D. Execute
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    • 7. The variation in the duration of the day and the night is due to earth's

    • Options
    • A. rotation on its axis
    • B. revolution around the sun
    • C. inclination of an angle of 60(1/2) degrees
    • D. both (a) and (b)
    • Discuss
    • 8. Velu Thampi led a revolt against the British in state of


    • Options
    • A. Travancore
    • B. Baroda
    • C. Hyderabad
    • D. Mysore
    • Discuss
    • 9. Another name for a computer chip is ...

    • Options
    • A. Execute
    • B. Micro chip
    • C. Microprocessor
    • D. Select
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    • 10. What is the length of each stump in the cricket?

    • Options
    • A. 35 inches
    • B. 22 inches
    • C. 28 inches
    • D. 33 inches
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