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  • Question
  • Which of the following statements is most accurate regarding infection with parvovirus B19?


  • Options
  • A. Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors
  • B. Parvovirus B19 can cause hydrops fetalis via transplacental infection of a fetus in a seropositive mother
  • C. Parvovirus B19 can be diagnosed by detection of viral RNA using PCR or hybridization assays
  • D. Parvovirus B19 replicates in the host cell nucleus utilizing a virally encoded DNA polymerase to create a double- stranded DNA intermediate

  • Correct Answer
  • Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors 

    Explanation

    Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors.

     

    a. Parvovirus B19 binds preferentially to the erythrocyte blood group P antigen on erythroid precursor cells.

    Answers B, C, D are incorrect:

    b. after entry the single-stranded viral DNA genome is transported to the cell nucleus where the host DNA polymerase synthesizes the complimentary DNA strand.

    c. Parvovirus B19 infection can be diagnosed by direct detection of viral DNA not RNA.

    d. the fetus of a seropositive mother is protected from infection by maternal circulating antibodies.

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    More questions

    • 1. What is an FET?

    • Options
    • A. Farad Effect Transformer
    • B. Field Effect Transformer
    • C. Field Effect Transistor
    • D. French Energy Transfer
    • Discuss
    • 2. The greatest variety of animal and plant species is fund in


    • Options
    • A. temperate grasslands
    • B. tropical moist forests
    • C. tundra regions
    • D. in hot deserts
    • Discuss
    • 3. The members of the Rajya Sabha are elected for a term


    • Options
    • A. of six years
    • B. determined by the state legislative assembly of a state
    • C. of four years
    • D. None of the above
    • Discuss
    • 4. The shallow seas found in the Atlantic basin include the

    • Options
    • A. Caribbean sea and Mediterranean
    • B. Baltic and Arctic seas
    • C. Gulf of Mexico
    • D. All of the above
    • Discuss
    • 5. Coral reefs in India can be found in

    • Options
    • A. the coast of Orissa
    • B. Waltair
    • C. Rameshwaram
    • D. Trivandrum
    • Discuss
    • 6. Which of the following is the lightest metal?

    • Options
    • A. Mercury
    • B. Lithium
    • C. Lead
    • D. Silver
    • Discuss
    • 7. The first graphical browser for the WWW was named:

    • Options
    • A. Netscape
    • B. Veronica
    • C. Mosaic
    • D. Explorer
    • Discuss
    • 8. What Designates where the next action occurs?

    • Options
    • A. Decode
    • B. Highlight
    • C. Select
    • D. Mother board
    • Discuss
    • 9. 'Eight Lives' is a book written by

    • Options
    • A. Raja Ramana
    • B. Savita Ambedkar
    • C. Mahesh Yogi
    • D. Raj Mohan Gandhi
    • Discuss
    • 10. In India the first television programme was broadcasted in

    • Options
    • A. 1959
    • B. 1965
    • C. 1976
    • D. 1957
    • Discuss


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