In medicinal chemistry, which of the following compounds is used as a standard anti malarial drug for the treatment and prevention of malaria?

Difficulty: Easy

Correct Answer: Chloroquin, an anti malarial drug (chloroquine)

Explanation:


Introduction / Context:
Malaria is a serious infectious disease caused by Plasmodium parasites transmitted by mosquitoes. Anti malarial drugs are used both for treatment and sometimes for prevention in high risk areas. One of the historically important and widely known drugs against malaria is chloroquine, which has been used for many years, especially against uncomplicated cases caused by certain Plasmodium species. This question asks you to identify which compound from the list is an anti malarial drug, contrasting it with drugs used for other medical purposes.


Given Data / Assumptions:

  • The options include aspirin, Neosporin, chloroquin, and antacid.
  • We interpret chloroquin as chloroquine, a standard spelling variant in some question banks.
  • We assume basic knowledge of common medicines and their primary uses.
  • The question is at a general knowledge level, not asking for detailed pharmacology.


Concept / Approach:
Chloroquine is a synthetic anti malarial drug that has been widely used to treat malaria, especially in regions where there is no significant resistance. It acts by interfering with the parasite haem metabolism in red blood cells. Aspirin is a common pain reliever and fever reducer, classified as an analgesic and antipyretic, and also used as an anti inflammatory and blood thinner. Neosporin is a brand name for a topical antibiotic cream used to prevent infection in minor cuts and burns. Antacids are medications that neutralise stomach acid to relieve heartburn and indigestion. Only chloroquine (chloroquin in this spelling) directly fits the description of an anti malarial drug.


Step-by-Step Solution:
Step 1: Identify that the question is asking for a compound used as an anti malarial drug. Step 2: Recall that chloroquine is well known as a medicine for the treatment and prevention of malaria. Step 3: Recognise that aspirin is mainly used for pain relief, fever reduction, and as an anti inflammatory agent, not as an anti malarial. Step 4: Note that Neosporin is a topical antibiotic preparation used on the skin, not for treating malaria. Step 5: Understand that antacids are used to neutralise stomach acid and relieve acidity and do not treat malaria. Step 6: Conclude that chloroquin (chloroquine) is the correct anti malarial drug and select it as the answer.


Verification / Alternative check:
Medical references and public health guides list chloroquine as one of the important drugs used in malaria treatment, particularly in areas where malaria parasites remain sensitive to it. It has been used both for treatment of acute attacks and for prophylaxis in travellers in some situations. Aspirin appears in sections on pain management and cardiovascular prevention. Neosporin is found in discussions of topical antibiotics, and antacids are covered under gastrointestinal medications. This clear separation of uses confirms that only chloroquin, meaning chloroquine, is the anti malarial agent among the options.


Why Other Options Are Wrong:
Aspirin does not act against malaria parasites and is not prescribed as an anti malarial drug. Neosporin is applied to the skin to prevent or treat bacterial infections in minor wounds, and has no role in systemic treatment of malaria. Antacids simply neutralise stomach acid, providing relief from heartburn and acidity, with no effect on parasitic infections. None of these compounds attacks the malaria parasite in the bloodstream, so they cannot be considered anti malarial drugs.


Common Pitfalls:
Some students may be tempted to choose aspirin because it is widely used for fever reduction, and malaria often presents with fever, but treating the symptom of fever is not the same as treating the underlying infection. Another pitfall is misunderstanding brand names like Neosporin, which might sound like a systemic drug but is actually topical. To avoid these mistakes, focus on whether the drug specifically targets the malaria parasite. Remember the association between chloroquine and malaria in exam questions on medicinal chemistry and public health.


Final Answer:
The compound used in an anti malarial drug is chloroquin, an anti malarial drug (chloroquine).

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