Biochemistry fundamentals — composition of enzymes From a biochemical standpoint, all classical enzymes are composed of which macromolecule class as their primary structural material?

Difficulty: Easy

Correct Answer: Proteins

Explanation:


Introduction / Context:
Enzymes are biological catalysts that accelerate reactions under mild conditions with high specificity. Knowing their chemical nature helps in understanding denaturation, pH effects, and active-site chemistry.


Given Data / Assumptions:

  • Classical enzymes in cells are macromolecular catalysts built from polypeptide chains.
  • Coenzymes or cofactors (metal ions, vitamins) may assist but are not the primary macromolecule.


Concept / Approach:
Proteins are polymers of amino acids. The three-dimensional structure (primary to quaternary) dictates catalytic function. While “amino acids” are the building blocks, the enzyme itself is a protein macromolecule, not free amino acids. Exceptions like ribozymes exist (RNA catalysts), but in standard curricula, enzymes are proteins.


Step-by-Step Solution:
Identify enzyme macromolecule → protein.Distinguish from building blocks (amino acids) and from other biomolecules (lipids, carbohydrates).Therefore, the correct choice is “Proteins.”


Verification / Alternative check:
Textbooks define enzymes as protein catalysts, with ribozymes taught as special RNA-based catalysts.


Why Other Options Are Wrong:

  • Fats: function in membranes/energy storage, not catalytic proteins.
  • Carbohydrates: structural/energy roles; not the enzyme scaffold.
  • Amino acids: monomers, not the assembled macromolecule.


Common Pitfalls:

  • Citing “amino acids” because they are components; the question asks about the macromolecule class.


Final Answer:
Proteins

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