In animal reproduction and assisted reproductive technology (ART), what does the term “superovulation” specifically refer to? Choose the option that best describes how the ovulatory response is achieved and regulated.

Biotechnology Animal Breeding and Transgenic Animal Difficulty: Easy
Choose an option
  • A
    Increased ovulatory response by external hormonal therapy
  • B
    Decreased ovulatory response by external hormonal therapy
  • C
    Decreased ovulatory response by internal hormonal therapy
  • D
    Increased ovulatory response by internal hormonal therapy
  • E
    No change in ovulatory response under any therapy

Answer

Correct Answer: Increased ovulatory response by external hormonal therapy

Explanation

Introduction / Context:Superovulation is a cornerstone in animal breeding and assisted reproductive technology (ART). It aims to obtain multiple ovulations in a single estrous cycle, thereby increasing the number of available oocytes or embryos for procedures such as artificial insemination, in vitro fertilization, and embryo transfer.

Given Data / Assumptions:

  • The question asks for a definition-level understanding.
  • External hormonal therapy typically includes exogenous gonadotropins (FSH, eCG) and synchronization agents.
  • Objective: increase the count of mature follicles that ovulate in one cycle.

Concept / Approach:

Physiologically, only a limited cohort of follicles proceeds to ovulation. Administering exogenous gonadotropins rescues additional follicles from atresia, yielding multiple ovulations. Protocols often combine follicle-stimulating hormone with prostaglandins or progesterone devices to synchronize timing for oocyte recovery or insemination.

Step-by-Step Solution:

Identify the goal: increase the number of ovulations per cycle.Map the mechanism: give exogenous gonadotropins to stimulate folliculogenesis.Clarify “external”: hormones are supplied from outside the animal (injections or implants).Conclude: superovulation = increased ovulatory response by external hormonal therapy.

Verification / Alternative check:

Breeding manuals and ART protocols consistently define superovulation as multi-ovulation induced by exogenous hormones, typically FSH-based regimens, sometimes with eCG and synchronization aids.

Why Other Options Are Wrong:

(b) and (c) describe decreased ovulation, the opposite of the aim. (d) “internal hormonal therapy” is vague; endogenous hormones are not what is administered. (e) contradicts clinical practice which clearly changes ovulatory response.

Common Pitfalls:

Confusing superovulation with superfertility or with just estrus synchronization; ignoring that dosing and timing critically affect embryo quality, not just quantity.

Final Answer:

Increased ovulatory response by external hormonal therapy

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