Cellular respiration — In eukaryotic cells, where does electron transport (the electron transport chain responsible for oxidative phosphorylation) occur?

Difficulty: Easy

Correct Answer: Membranes (specifically the inner mitochondrial membrane) and mitochondria

Explanation:


Introduction / Context:
Electron transport uses a chain of redox centers embedded in a membrane to convert the energy of electrons into a proton gradient that powers ATP synthase. Correctly localizing this machinery in eukaryotes is fundamental to understanding oxidative phosphorylation.


Given Data / Assumptions:

  • The mitochondrial inner membrane houses complexes I–IV and ATP synthase.
  • Electron carriers include ubiquinone (coenzyme Q) and cytochrome c.
  • Protons are pumped from the mitochondrial matrix to the intermembrane space.


Concept / Approach:
Match process to organelle and membrane. The eukaryotic ETC operates on the inner mitochondrial membrane. While photosynthetic eukaryotes also have a photosynthetic electron transport chain in thylakoid membranes (chloroplasts), the question refers to respiratory electron transport for ATP production in most eukaryotic cells, which is mitochondrial, not ER or cytosolic.


Step-by-Step Solution:

Locate the ETC: inner mitochondrial membrane (not ER or cytosol).Recognize proton pumping across this membrane establishes the electrochemical gradient.ATP synthase in the same membrane uses the gradient to synthesize ATP in the matrix.


Verification / Alternative check:
Electron micrographs and biochemical fractionation show ETC proteins in mitochondrial cristae membranes; ER lacks the respiratory chain complexes I–IV.


Why Other Options Are Wrong:

b) ER does host redox enzymes (e.g., P450s) but not the respiratory ETC.c) Cytoplasm lacks the membrane-bound chain required for proton pumping.d) Including ER and cytoplasm makes the statement incorrect.e) The nuclear envelope is not the site of respiratory electron transport.


Common Pitfalls:
Conflating mitochondrial electron transport with other cellular redox systems (peroxisomes, ER detoxification).


Final Answer:
Inner mitochondrial membrane in mitochondria.

More Questions from TCA Cycle

Discussion & Comments

No comments yet. Be the first to comment!
Join Discussion