Question 1

For the unfolding reaction of Protein G, ∆H° =210.6 kJ/mol, this means that

Accepted Answer

folding is favored enthalpically

Question 2

The correlation between free energy ΔG transfer between the aqueous/organic phases and the surface area of amino acid residues

Accepted Answer

reflects the reduction in solvent-accessible area during protein folding

Question 3

Buried hydrophobic side chains in a globular protein fit into a hole formed by the side chains of

Accepted Answer

5-7 other amino acids

Question 4

Unpaired H-bond donors and acceptors are found in the hydrophobic core of a protein

Accepted Answer

rarely

Question 5

Since ΔG° = -RTlnK

Accepted Answer

a 10-fold increase in K decreases ΔG° by about 2.3*RT

Question 6

At the midpoint of a temperature transition curve,

Accepted Answer

All of these

Question 7

Which of the following is the most correct?

Accepted Answer

Charged amino acids are seldom buried in the interior of a protein

Question 8

Which of the following forces is the most unfavorable for protein folding?

Accepted Answer

Conformational entropy

Question 9

Attractive Vander Waals forces occur between

Accepted Answer

any pair of nearby atoms

Question 10

Which of the following forces is the most favorable for protein folding?

Accepted Answer

Hydrophobic Interactions

Question 11

If the egg white protein, ovalbumin, is denatured in a hard-boiled egg, then which of the following is least affected?

Accepted Answer

The primary structure of ovalbumin

Protein Stability Questions