Essential RNAs for translation — which molecules are required? During protein synthesis in cells, which of the following RNA types are required for the process to proceed?

Difficulty: Easy

Correct Answer: All of these (tRNA, mRNA, and rRNA)

Explanation:


Introduction:
Translation converts genetic information into protein. Three RNA types play indispensable roles: mRNA carries the codon template, tRNA delivers amino acids via anticodons, and rRNA forms the structural and catalytic core of the ribosome.



Given Data / Assumptions:

  • mRNA encodes the amino acid sequence via codons.
  • tRNA acts as an adaptor linking codons to amino acids.
  • rRNA provides both scaffold and catalytic peptidyl transferase activity.


Concept / Approach:

Because each RNA type fulfills a nonredundant function, translation requires all three simultaneously. Removing any one stalls the process: without mRNA there is no template, without tRNA there is no delivery, and without rRNA there is no ribosome or catalysis.


Step-by-Step Solution:

mRNA binds the small subunit and defines the reading frame.tRNAs decode codons and carry amino acids to the A site.rRNA in the large subunit catalyzes peptide bond formation, extending the chain.The cycle repeats codon by codon until termination.


Verification / Alternative check:

Depletion or inhibition of any of these RNA classes halts translation in vivo and in vitro, demonstrating their essentiality.


Why Other Options Are Wrong:

Each single-RNA option omits required partners; snRNA participates mainly in pre-mRNA splicing, not cytosolic translation.


Common Pitfalls:

Assuming ribosomal proteins, rather than rRNA, provide the principal catalytic activity.


Final Answer:

All of these (tRNA, mRNA, and rRNA)

Discussion & Comments

No comments yet. Be the first to comment!
Join Discussion