If 'P' means '+', 'Q' means 'x', 'R' means '÷' and 'S' means '-', then 44 Q 9 R 12 S 6 Q 4 P 16 =?

After replacing all the symbol from question.
44 x 9 ÷ 12 - 6 x 4 + 16 = ?
Apply BODMAS rule,
⇒ 44 x 9 x 1/12 - 24 + 16 = ?
⇒ 33 - 24 + 16 = ?
⇒ 49 - 24 = ?
∴ ? = 25