Timing of mitotic stages Which mitotic phase is typically the shortest in duration during a normal somatic cell cycle?

Introduction / Context:
Mitosis is subdivided into prophase, prometaphase, metaphase, anaphase, and telophase. The relative duration of each informs how frequently cells are observed in each stage under the microscope and reflects underlying mechanics.

Given Data / Assumptions:

• Chromosome alignment at metaphase requires time for tension and checkpoint satisfaction.
• Anaphase is a rapid separation and movement event.
• Interphase is not part of mitosis and is much longer.

Concept / Approach:
Once all kinetochores are correctly attached and the spindle assembly checkpoint is satisfied, separase triggers cohesin cleavage, and chromatids move swiftly poleward. This phase—anaphase—typically lasts the shortest interval compared with the set-up (metaphase) and wrap-up (telophase).

Step-by-Step Solution:

Verification / Alternative check:
Time-lapse microscopy in model cells consistently shows anaphase as brief relative to other mitotic stages.

Why Other Options Are Wrong:

• Interphase is not a mitotic phase and is much longer.
• Metaphase persists until checkpoint satisfaction.
• Prophase and telophase involve structural assembly/disassembly that takes longer.

Common Pitfalls:
Including interphase when asked specifically about mitotic phases.

Final Answer:
Anaphase