Difficulty: Easy
Correct Answer: Tryptophan, tyrosine, glutamine, asparagine
Explanation:
Introduction / Context:
One-letter codes are widely used in bioinformatics, structural biology, and sequence annotation. Accurate decoding ensures correct interpretation of motifs, domains, and mutational data across databases.
Given Data / Assumptions:
Concept / Approach:
Memorized mappings (e.g., “Queen Q = glutamine,” “New N = asparagine,” “Why Y = tyrosine,” “Double ring W = tryptophan”) help recall. Care must be taken not to confuse Q (glutamine) with E (glutamic acid) or N (asparagine) with D (aspartic acid).
Step-by-Step Solution:
Verification / Alternative check:
Compare with standard IUPAC tables of one-letter amino-acid codes; W, Y, Q, N are unambiguous.
Why Other Options Are Wrong:
Common Pitfalls:
Confusing amide forms (Q, N) with their acidic counterparts (E, D). The side-chain amides are neutral at physiological pH, unlike their acidic forms.
Final Answer:
Tryptophan, tyrosine, glutamine, asparagine
Discussion & Comments