In this sentence improvement item, choose the best replacement for the bracketed word "(inspite)" in the sentence "Our destiny is always and only in our own hands, inspite all apparent evidence which may indicate otherwise."

Introduction / Context:
This question tests your knowledge of the correct form of a very common contrast word used in formal English. The sentence talks about personal destiny remaining in our hands, even when evidence seems to suggest otherwise. The bracketed form "inspite" is a frequent spelling and usage error, and your task is to choose the correct alternative that fits naturally before "all apparent evidence".

Given Data / Assumptions:

• Original segment: "inspite all apparent evidence which may indicate otherwise".
• The intended meaning is similar to "in spite of all apparent evidence".
• Options include "despite in", "despite of", "despite", and "No improvement".
• We need a single word or phrase that introduces contrast correctly.

Concept / Approach:
Standard English uses "despite" as a single word meaning almost the same as "in spite of". It is followed directly by a noun or noun phrase, such as "despite the rain" or "despite all evidence". The incorrect one word form "inspite" is not used in formal writing. Similarly, "despite of" is wrong because "of" already appears in the phrase "in spite of". In this question, "despite" followed immediately by "all apparent evidence" gives exactly the formal, concise expression we need.

Step-by-Step Solution:
Step 1: Recognise that "inspite" is a wrong or non standard form. Step 2: Recall that there are two correct contrast forms: "despite" and "in spite of". Step 3: Note that the sentence structure requires a word directly before "all apparent evidence". Step 4: Choose "despite" so the phrase becomes "despite all apparent evidence". Step 5: Confirm that this version is concise, formal, and grammatically correct.

Verification / Alternative check:
Try inserting each option into the sentence. "Despite in all apparent evidence" is clearly incorrect because it contains two prepositions in a row. "Despite of all apparent evidence" is also wrong, as "of" does not follow "despite". Leaving "inspite" unchanged keeps the error. Only "despite all apparent evidence" matches the forms taught in grammar books and used in newspapers, academic writing, and competitive exam passages.

Why Other Options Are Wrong:
"Despite in" mixes two prepositions and never occurs as a fixed expression.

"Despite of" incorrectly combines "despite" with "of" and is considered wrong in standard English.

"No improvement" cannot be correct because "inspite" is not an accepted spelling or form; the correct phrase is "in spite of".

Common Pitfalls:
Many learners confuse "despite" and "in spite of" and sometimes create hybrid forms like "despite of" or "inspite". A simple rule is to remember that "despite" stands alone and is never followed by "of", while "in spite of" is a three word expression that always includes "of". When you need a single word before a noun phrase, "despite" is usually the right choice. When you want to use a multi word phrase, use "in spite of".

Final Answer:
The correct improvement is "despite", giving the phrase "despite all apparent evidence which may indicate otherwise".