Difficulty: Medium
Correct Answer: Paracentric inversion (excludes the centromere)
Explanation:
Introduction / Context:
Inversions alter the linear order of genes and can produce meiotic complications. Whether the centromere is included in the inverted segment determines the products of crossing over and the viability of resulting gametes. This question probes your ability to link cytogenetic configurations to meiotic outcomes.
Given Data / Assumptions:
Concept / Approach:
In a paracentric inversion, a crossover within the loop generates one dicentric chromatid (two centromeres) and one acentric fragment (no centromere). The dicentric can form a bridge that breaks; the acentric is lost, often causing gamete inviability. In pericentric inversions, crossovers yield chromatids with duplications and deletions but not dicentric/acentric products because the centromere is included in the exchanged segments.
Step-by-Step Solution:
Verification / Alternative check:
Cytology textbooks consistently illustrate paracentric crossovers with bridges and fragments at anaphase I; pericentric events instead create duplication/deletion chromatids that retain single centromeres.
Why Other Options Are Wrong:
Common Pitfalls:
Memorizing outcomes without distinguishing whether the centromere lies inside or outside the inversion loop.
Final Answer:
Paracentric inversion (excludes the centromere)
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