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Which of the following statements about ddntps is true?

They have a hydrogen at the 3’ carbon of the sugar.
DNA polymerase can add a new dNTP to a 3’ ddNTP.
They have a free 3’-hydroxyl group on the ribose sugar.
They have an oxygen at the 2’ carbon of the ribose sugar.

Correct Answer: They have a hydrogen at the 3’ carbon of the sugar.

Explanation:

ddNTPs - Dideoxynucleotides and abbreviated as ddNTPs.

They are chain-elongating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing.

They have a hydrogen at the 3’ carbon of the ribose sugar.

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