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Home Biochemistry Cell Signalling and Transduction Comments

  • Question
  • Which of the following processes involve the combining of a message from one signaling molecule with that of another to either enhance or inhibit a cellular effect?


  • Options
  • A. Signal transduction
  • B. Signal reception
  • C. Signal integration
  • D. Signal amplification

  • Correct Answer
  • Signal integration 


  • Cell Signalling and Transduction problems


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    • 1. cAMP and cGMP are derived from

    • Options
    • A. ATP and GTP by the actions of adenylate cyclase and guanylate cyclase respectively
    • B. GTP and ATP by the actions of adenylate cyclase and guanylate cyclase respectively
    • C. ATP and GTP by the actions of guanylate cyclase and adenylate cyclase respectively
    • D. none of the above
    • Discuss
    • 2. Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

    • Options
    • A. mimics the action of signal receptors
    • B. is broken down into hormones that affect the heart
    • C. interferes with chemical cascades that trigger contraction of heart muscle
    • D. breaks down into nitric oxide, which increases blood flow to the heart
    • Discuss
    • 3. When a __________ reaches its __________ , there is a specific means of receiving it and acting on the message. This task is the responsibility of specialized proteins called __________ .

    • Options
    • A. signaling molecule; receptor; G proteins
    • B. signaling molecule; target cell; G proteins
    • C. signaling molecule; target cell; receptors
    • D. kinase; receptor; proteases
    • Discuss
    • 4. Which of the following is not a type of signaling molecule?

    • Options
    • A. Testosterone
    • B. Insulin
    • C. Thyroxin
    • D. Adenylate cyclase
    • Discuss
    • 5. Self-phosphorylation is an excellent mechanism for triggering specific catalytic function of the proteins involved in signal cascades because it

    • Options
    • A. changes the shape and thus the enzymatic activity of the proteins involved
    • B. makes the receptor more likely to capture the signaling, molecule
    • C. allows hydrophilic signaling molecules to cross the plasma membrane
    • D. None of the above
    • Discuss
    • 6. Which of the following statements about G proteins is false?

    • Options
    • A. They are involved in signal cascades
    • B. They bind to and are regulated by guanine nucleotides
    • C. They become activated when bound to GDP
    • D. They must be active before the cell can make needed cAMP
    • Discuss
    • 7. A cell is known to respond to a particular signaling molecule. Which of the following must be true of this cell?

    • Options
    • A. It is in the heart muscle
    • B. It is also the site of production for the signaling molecule
    • C. It contains the receptor for the signaling molecule
    • D. It is incapable of signal transduction
    • Discuss
    • 8. The signaling molecules called steroid hormones

    • Options
    • A. are made in one location of the body but have their effects some distance away
    • B. are hydrophilic and so cannot penetrate the plasma membrane
    • C. bind to cell surface receptors to trigger chemical cascades
    • D. never enter the blood of humans
    • Discuss
    • 9. In the signal transduction mechanism known as protein phosphorylation

    • Options
    • A. the signaling molecule binds to a surface receptor
    • B. receptor kinases play a key role in triggering the signal cascade
    • C. phosphorylated proteins act with enzymes to trigger the signal cascade
    • D. All of the above
    • Discuss
    • 10. Which of the following is a hormone whose action requires a cell surface receptor?

    • Options
    • A. Nitric oxide
    • B. Progesterone
    • C. Adrenaline
    • D. Growth factors
    • Discuss


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